NOTE: Recently, the ministry has approved funding for a follow-up project: "ControlAR: Model-based process engineering to CONTROL Antimicrobial Resistance for the food industry 4.0". RTI2018-093560-J-I00 (MCIU/AEI/FEDER, UE). WEB PAGE
The project at a glance
The five Ws and one H (essential questions when gathering information)
- This is a three-year project for the "Development of models and efficient numerical tools for the control of bacterial RESISTANCE to antimicrobials in the food industry". The idea is funded by the Ministry of Economy and Competitiveness in collaboration with the European Regional Development Fund (Proyectos de I+D+I para jóvenes investigadores sin vinculación o con vinculación temporal Dirección General de Investigación Científica y Técnica Subdirección General de Proyectos de Investigación, DPI2014-54085-JIN)
- Resistance of bacteria to antimicrobials is a current concern in Europe and world-wide as is
stressed by the scientific community and contemplated in different regulations. As a result,
the food industry has become over-conservative in applying biocide treatments. While the
use of new technologies such as active packaging could reduce the use of biocides, further
research is needed in this area and currently their application is very limited in the industry.
Nevertheless, despite the high concentrations of biocides generally used, studies in food
factories have detected persistent and resistant strains of microorganisms, which will
decrease the effectiveness of future biocide-treatments. Moreover, these resistant bacteria
could potentially contaminate food and not only reduce its shelf-life, but also contribute to
increase the resistance to antibiotics, which is one of the main concerns in medical research.
As a consequence, the food industry should start considering biocide-resistance in their risk
assessment and management procedures.
The development of new software to detect and control risk probability of bacterial infection
and resistance may contribute substantially to risk assessment and management, resulting in
safer and healthier food products. In addition, these techniques are tested on different case studies of interest for the food industry.
Last but not least, resulting models of biocide-resistance could contribute to the
understanding of antibiotic resistance, which has wide implications in the treatment of
- Principal Investigator: Míriam R. García1
In collaboration with: Marta López Cabo2, Xosé A. Vázquez, Eva Balsa Canto1 and Antonio A. Alonso1
- 1Bioprocess Engineering Group and 2 Microbiology and Technology of Marine products. IIM - CSIC, Vigo Spain
- Starting 16 October 2015.
News & Events
- Oct. 2018
- Sep. 2018
Attending the Spanish Annual Workshop in Automatica ( XXXIX Jornadas de Automática) to present a work in collaboration with Miguel Mauricio about "Computer-Aided Design of Active Packaging/Food System for extended shelf life"
- Jul. 2018
- Jun. 2018
- Míriam R. García will visit the Department of Mathematics at the Imperial College London for 3 weeks to collaborate with
- Diego Oyarzún to control the Morbidostat dynamics
- Philipp Thomas to estimate different bacterial growth aspects using DNA flow cytometry distributions
- Andrea Weisse (NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance) to study evolution of resistance in different environments
- May. 2018
- Apr. 2018
- Attending the 10th biennial FOODSIM2018 where we talked about:
- Smart Sensors to assess and to anticipate Fish Quality Evolution
- Stochastic Methods to model Bacterial Growth and Food Safety Risks: Some Perspectives
- Mar. 2018
- Jan. 2018
- Dec. 2017
- Nov. 2017
- The Science Week Eva Balsa-Canto and Míriam R. García with other members of the Bioprocess Engineering Group presented the street fair "the maths that feeds us"
- Oct. 2017
- Sept. 2017
- Aug. 2017
- Our work "New model of ATP degradation to accurately predict fish quality and reduce food waste" was selected to be presented as oral talk in the EFFoST conference .
- Jun. 2017
- Attending the PACBB (11th International Conference on Practical Applications of Computational Biology & Bioinformatics).
- May. 2017
- Our works were selected for the 10th International Conference of Predictive Microbiology in Food (2 oral talks and 1 poster):
- Modelling biocide and bacteria interaction in chemical disinfection
- Estimating bacterial population growth rates from flow cytometry
- Modelling and identification of relevant pathways for nucleotide degradation in fresh hake during storage
- Mar. 2017
- Dec. 2016
- Nov. 2016
- Oct. 2016
- Attending the FOSBE (International Federation of Automatic Control).
- Sep. 2016
- Aug. 2016
- Jul. 2016
- Our work was selected for a IFAC conference talk. The research focused on modelling cell size variability using flow cytometry and it will be presented in October in FOSBE
- Attending the FoodMicro 2016 Conference. Here we present a poster about designing a smart sensor for predicting cod quality and shelf-life (Poster) . They were very interesting sessions about AMR and Risk analysis, see the abstracts of the conference here
- Jun. 2016
- Jorge Macridachis has started his Master intership. During three months he will model the growth of Lactococcus lactis, one of the most important microorganisms in the dairy industry. Using the software AMIGO2 and experimental data provided by our collaborator Marta López Cabo, he will explore aspects related with parameter uncertainty and optimal experimental desing.
- May 2016
- Mar. 2016
- Nov. 2015
- Oct. 2015
Updated by Míriam R. García