Wellcome to Míriam R. García webpage (till 2022). We have moved to this New Webpage
My name is Míriam Rodríguez García. I am a Tenured Scientist at the Biosystems and Bioprocess Engineering Group (IIM - CSIC).
I am PI of the project "ControlAR: Model-based process engineering to CONTROL Antimicrobial Resistance for the food industry 4.0" (Web page ControlAR). RTI2018-093560-J-I00 (MCIU/AEI/FEDER, UE).
This project is a continuation of "RESISTANCE: Development of models and efficient numerical tools for the control of bacterial RESISTANCE to antimicrobials in the food industry" (Web page RESISTANCE). DPI2014-54085-JIN
For more information you can
Education
Past Institutions
Breaks
News and Events of the group
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We have stopped reporting news and events as we have moved to a New Webpage, included in our (also new) Group Webpage.
- Nov. 2021
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- Míriam R. García becomes Tenured Scientist, (More info).
- Oct. 2021
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- Our work Development of a toxicokinetic-toxicodynamic model simulating chronic copper toxicity to the Zebra mussel based on subcellular fractionation was published in Aquatic Toxicology. This is an outcome of our collaboration with T.T. Yen Le on developing Toxicokinetic-toxicodynamic models.
- Sep. 2021
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- Attending XLII Jornadas de Automática Castellón 2021 to present our group "Comparing Stochastic MOdels of Bacterial Growth at Different scales (only abstract in English)". Download the work in this link
- Jul. 2021
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- Adrián Pedreira was interviewed by our regional television in Galicia Link to interview
- Jun. 2021
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- Our work Modelling chronic toxicokinetics and toxicodynamics of copper in mussels considering ionoregulatory homeostasis and oxidative stress was published in Enviromental Pollution. This is an outcome of our collaboration with T.T. Yen Le on developing Toxicokinetic-toxicodynamic models.
- Adrián Pedreira attended the Spanish annual congress of microbiology (XXVIII CONGRESO NACIONAL DE MICROBIOLOGÍA) to present the potential of the morbistat to study bacterial stress with antimicrobials.
- May. 2021
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- We welcome Nerea Martínez López to our group. She is a PhD student and will work on multi-scale modelling of bacterial dynamics with antimicrobials.
- Apr. 2021
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- Adrián Pedreira has presented his work "Morbidostato: descifrando la evolución de poblaciones bacterianas sometidas a estrés por antimicrobianos" in the workshop "Jornada Virtual de Doctorandos MSO" (modelado simulación y optimización) 2021
- Mar. 2021
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- We hare happy to anounce that the proyect 20213AT001 Atracción de Talento para RYC2019 (proyectos intramurales especiales CSIC) starts this month. The title and the objective is the development of "Multiscale mechanistic dynamic modelling of the CHEmical and biochemical effect on the growth and death of BACteria (ChemBac)"
- We welcome Jose Antonio Férez to our group. He has been working on different statistical methods (Multivariable analysis, Bayesian Networks...) applied to medicine.
- Míriam R. García has been working within the “Global Health” Interdisciplinary Platform (PTI-CSIC) to publish a newer version of the book Una visión global de la pandemia COVID-19: qué sabemos y qué estamos investigando desde el CSIC. The updated version can be read in Spanish here
- Feb. 2021
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Publication of the EFSA Scientific Option ( The use of the so‐called ‘superchilling’ technique for the transport of fresh fishery products ) by the Working Group on the transport/storage of fresh fishery products.
In the study we used a Heat Transfer model to determine the conditions of superchilling (Superchilling fresh fishery products SFFP) to assure that fish temperatures are bellow temperatures when fish is transported with ice (conventional fresh fishery products, CFFP). As a result we developed a tool that can be used as part of 'safety-by-design' approach of the food business operator to identify safe SFFP desings named Heat transfer model tool for the heat absorption capacity of superchilled fresh fishery products (HTM-SFFP Tool) - Our "Critical Review of Disinfection Processes to Control SARS-CoV-2 Transmission in the Food Industry" was finally accepted for publication in the Foods journal. This was a collaboration between Adrián Pedreira and Míriam R. García with Yeşim Taşkın (with a EIT Food RIS Fellowship in our group). The review discussed the importance of considering the one-health approach when optimizing disinfection, and avoid misused and overused of disinfectants that may act as drivers of antimicrobial bacterial resistance.
- We have presented our Morbidostat in the annual gathering of our Institute (Encontrols IIM: segunda fase), with a POSTER about "The Morbidostat. Unravelling bacterial evolution under antimicrobial stress". The poster was presented by Adrián Pedreira (follow his twitter account @adrian_pedreira for updates about the device)
- Míriam R. García has started his contract as Ramón y Cajal fellow (RYC2019-028006-I/AIE/10.13039/501100011033)
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Publication of the EFSA Scientific Option ( The use of the so‐called ‘superchilling’ technique for the transport of fresh fishery products ) by the Working Group on the transport/storage of fresh fishery products.
- Jan. 2021
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- Míriam R. García was speaking about Systems Engineering in the food industry in the 3er Seminario Multidisciplinar en Ciencias e Ingeniería @UTEM 2021. A seminar organised by Faculty of Engineering of the Universidad Tecnológica Metropolitana. See flyer here
- Nov. 2020
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- We have published the data-sheet with the disinfectants tested against SARS-CoV-2 and other coronaviruses in the zenodo platform in https://doi.org/10.5281/zenodo.4297322
- Oct. 2020
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- We are happy to announce that Míriam R. García has passed the selection procedure to be tenured Research Scientist in the CSIC.
- Sep. 2020
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- We welcome Adrián Pedreira Bar. He has started working in our group as a PhD student to develop predictive models of inactivation by disinfectants. The fellowship was funded by the Xunta de Galicia.
- Aug. 2020
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- Due to the unexpected COVID-19 pandemic, we have been actively revising the literature and some results were included in the book Una visión global de la pandemia COVID-19: qué sabemos y qué estamos investigando desde el CSIC
- Jul. 2020
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- We welcome Yeşim Taşkın. She will work with us for 4 months to study how to design optimal protocols of disinfection in the food industry. She is founded by the EIT Food RIS Fellowships
- We are happy to announce that Míriam R. García was selected for the Ramón y Cajal fellowship in the 1st position of the area of Industrial production, civil engineering and engineering for societies.
- May. 2020
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- Due to the unexpected COVID-19 pandemic, we have been actively revising the literature and publishing some press articles in Spanish such as ¿Cuál es el riesgo de contraer COVID-19 en un ascensor?
- Apr. 2020
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- Publication of the EFSA Scientific Option ( The use of the so‐called ‘tubs’ for transporting and storing fresh fishery products ) by the Working Group on the transport/storage of fresh fishery products. Together with the publication, some members of the group published the CODE to simulate temperature dynamics and spatial distribution when fish is transported or stored in Tubs (with water and ice) and Boxes (with only ice)
- March. 2020
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- Short comment about the aim of ControlAR research project in the Spanish News
- Feb. 2020
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- Published our work about Hyaluronic acid of tailored molecular weight by enzymatic and acid depolymerization in the journal of International Journal of Biological Macromolecules.
- Jan. 2020
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- Accepted our work about Model-based design of smart active packaging systems with antimicrobial activity in the journal of Food Packaging and Shelf Life. Link to article. The code is available here
- We welcome Marín Pérez to our research team. He will be using molecular dynamics to elucidate the mechanisms of disinfection of Chloride of Benzalkonium.
- Dec. 2019
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- Participating in the annual gathering of our Institute (Encontrols IIM: primeira fase), with a poster about food safety modelling.
- Nov. 2019
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- Accepted our work about Marine chondroitin sulfate of defined molecular weight by enzymatic depolymerization in the journal of Carbohydrate Polymers.
- Sep. 2019
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- Accepted our work about Mechanistic simulation of bioconcentration kinetics of waterborne Cd, Ag, Pd, and Pt in the zebra mussel Dreissena polymorpha in the journal Chemosphere.
- Attending 11th International Conference on Predictive Modelling in Food Bragança, Portugal. We presented two works
- Starting the module of Optimization and Control in the "Máster en Matemática Industrial". Department of mathematics, university of Vigo.
- Attending XL Jornadas Nacionales de Automática Ferrol 2019
- The ControlAR project starts: "ControlAR: Model-based process engineering to CONTROL Antimicrobial Resistance for the food industry 4.0". RTI2018-093560-J-I00 (MCIU/AEI/FEDER, UE)
- Jul. 2019
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- We congratulate and wish the best of luck to Laura Honrubia. She defended her end-of-degree project to obtain the degree of BSc Biomedical Sciences (Universitat de Lleida) with the second-best mark. Her work was focused on "Optimization of Benzalkonium Chloride treatment in the disinfection of L. monocytogenes in the Food Industry". See document here
- Jun. 2019
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- Research Funding We are happy to announce that the Spanish Ministry of Science, Innovation and Universities has approved funding for the following research project: "ControlAR: Model-based process engineering to CONTROL Antimicrobial Resistance for the food industry 4.0". RTI2018-093560-J-I00 (MCIU/AEI/FEDER, UE)
- As an EFSA external expert, I have participated in the 3rd meeting of the working group on the use of "tubs" for fresh fishery products
- May. 2019
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- I have assisted to the "New Vistas in Computational Systems and Synthetic Biology". The group where I work (Process Engineering group IIM-CSIC) organised this interesting international workshop that counted with speakers such as Hidde de Jong, Mustafa Khammash, Edda Klipp, Victor de Lorenzo, Jesús Picó, Julio Saez-Rodríguez, Pablo Carbonell... See the details here
- Kick-off meeting of the project SeafoodAge. This is an INTERREG project I am participating to "Smart and eco-innovative seafood processes and products for a healthy ageing. See updates here
- 2nd meeting of the working group on the use of "tubs" for fresh fishery products (minutes)
- Apr. 2019
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- I have participated as a specialist into the 147 European Study Group with Industry. A gathering of industrial scientists and academic mathematicians to work on problems affecting the industry. Our task was to identify control parameters of a wind turbine given its aeroelastic model, certain control logic and measurments of such turbine in operation
- Mar. 2019
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- I have been assigned the role of MEMBER in EFSA BIOHAZ WG on the use of "tubs" for fresh fishery products (M-2019-0023 /// EFSA-Q-2019-00053).
- Feb. 2019
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- For the International Day of Women and Girls in Science we (Irene Otero Muras and me) presented the street fair "the maths that feeds us" for kids of 10-12 years old
- Dic. 2018
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- First Editorial Work for Plos One. See my publons profile for more info
- Oct. 2018
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- Our on-going work in collaboration with the group of Recycling and valorisation of waste materials (REVAL) about "Production of defined molecular weight chondroitin sulfate of marine origin by enzymatic hydrolysis" was presented in the 1st NANOGATEWAY International Scientific Conference
- Sep. 2018
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- Attending the Spanish Annual Workshop in Automatica (XXXIX Jornadas de Automática) to present a work in collaboration with Miguel Mauricio about "Computer-Aided Design of Active Packaging/Food System for extended shelf life"
- Jul. 2018
- Jun. 2018
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- Míriam R. García will visit the Department of Mathematics at the Imperial College London for 3 weeks to collaborate with
- Diego Oyarzún to control the Morbidostat dynamics
- Philipp Thomas to estimate different bacterial growth aspects using DNA flow cytometry distributions
- Andrea Weisse (NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance) to study evolution of resistance in different environments
- Míriam R. García will visit the Department of Mathematics at the Imperial College London for 3 weeks to collaborate with
- May. 2018
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- Our work Optimization of E. coli inactivation by benzalkonium chloride reveals the importance of quantifying the inoculum effect on chemical disinfection was accepted for publication in the Frontiers in Microbiology, section Food Microbiology, research topic Foodborne Pathogens: Hygiene and Safety
- Apr. 2018
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- Attending the 10th biennial FOODSIM2019 where we talked about:
- Smart Sensors to assess and to anticipate Fish Quality Evolution
- Stochastic Methods to model Bacterial Growth and Food Safety Risks: Some Perspectives
- Attending the 10th biennial FOODSIM2019 where we talked about:
- Mar. 2018
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- Our work "Modeling the dynamics of antimicrobial resistance in a Morbidostat" was selected to be presented as oral talk in the 11th European Conference on Mathematical and Theoretical Biology 2019) .
- Jan. 2018
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- Attending the IV Simposio CEA de Modelado, Simulación Y Optimización. Here we will talk about "Mathematical modeling, simulation and optimization applied to food industry processes"
- Dec. 2017
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- Our work Stochastic individual-based modelling of bacterial growth and division using flow cytometry was accepted for publication in the Frontiers in Microbiology, section Systems Microbiology, research topic The Individual Microbe: Single-Cell Analysis and Agent-Based Modelling
- Nov. 2017
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- The Science Week Eva Balsa-Canto and Míriam R. García with other members of the Bioprocess Engineering Group presented the street fair "the maths that feeds us"
- Oct. 2017
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- Journal of Food Engineering has just accepted our research work "A mathematical model to predict early quality attributes in hake during storage at low temperature"
- Attending the EFFoST conference
- Sept. 2017
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- Attending 10th International Conference of Predictive Microbiology in Food. If you are around and interested in our work, please come to one of our talks or to our poster.
- Aug. 2017
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- Our work "New model of ATP degradation to accurately predict fish quality and reduce food waste" was selected to be presented as oral talk in the EFFoST conference
Follow the links to see latest news.
- Attending the PACBB (11th International Conference on Practical Applications of Computational Biology & Bioinformatics).
- Our works were selected for the 10th International Conference of Predictive Microbiology in Food (2 oral talks and 1 poster):
- Modelling biocide and bacteria interaction in chemical disinfection
- Estimating bacterial population growth rates from flow cytometry
- Modelling and identification of relevant pathways for nucleotide degradation in fresh hake during storage
- Our work was selected for the International Conferencee on Practical Applications of Computational Biology & Bioinformatics . The research focused on a normalisation strategy to optimally design experiments in computational biology. The methodology is validated in a model simulating the bacterial SOS response
- Journal of food engineering has accepted our paper "A model for the biochemical degradation of inosine monophosphate in hake (Merluccius merluccius)" (Article link, Eprint link)
- Journal of food engineering has accepted our paper "Smart sensor to predict retail fresh fish quality under ice storage" (Article link, Eprint link)
- Attending the FOSBE (International Federation of Automatic Control).
- Attending the IFAC Workshop on Thermodynamic Foundation of Mathematical Systems Theory.
- Attending the EMBO workshop of Cell Size regulation.
- Another of our works was selected for a IFAC workshop talk. In the IFAC Workshop on Thermodynamic Foundation of Mathematical Systems Theory Míriam R. García will talk about individual-based models using the modified Fokker-Planck equation.
- Our work was selected for a IFAC conference talk. The research focused on modelling cell size variability using flow cytometry and it will be presented in October in FOSBE
- Attending the FoodMicro 2016 Conference. Here we present a poster about designing a smart sensor for predicting cod quality and shelf-life (Poster) . They were very interesting sessions about AMR and Risk analysis, see the abstracts of the conference here
- Jorge Macridachis has started his Master intership. During three months he will model the growth of Lactococcus lactis, one of the most important microorganisms in the dairy industry. Using the software AMIGO2 and experimental data provided by our collaborator Marta López Cabo, he will explore aspects related with parameter uncertainty and optimal experimental desing.
- Critical Reviews in Food Science and Nutrition (ranked 2nd among journals of Food Science and technology, IF 2015: 5.492) has accepted our research work "Towards predictive food process models: A protocol for parameter estimation"
- Our abstract "Modelling microbial spoilage as the bases to predict fish quality indexes" has been accepted in the 25th International ICFMH Conference - FoodMicro 2016
- The Science Week Eva Balsa-Canto and Míriam R. García with other members of the Bioprocess Engineering Group presented the street fair "the maths that feeds us"
- Attending the 29th EFFoST International Conference. Here we present a poster analysing the influence of microorganisms in fish shelf-life using microbiology modelling ("Prediction and assessment of retail hake freshness during storage"). We also contibute with another work entitled "Towards Predictive models in Food Engineering: Dos and Don'ts"
- Attending the BioMicroWorld Conference. There were several interested talks related with the experimental workpackage of the project (WP1: Analytical techniques and experiments). Most of these talks were included in the conference's hot topic "Antimicrobial agents and chemotherapy. Antimicrobial resistance".
In this conference Graciela Ramilo also presented two posters: "Biocontrol of Staphylococcus aureus by bacteriophage K in the food industry" and "Assessment of tolerance development in L. monocytogenes-E. coli dual-species biofilms to Pronase and Benzalkonium chloride treatment"